Standard precautions are the foundation of infection prevention: every patient, every encounter, every time. The CDC framework assumes that blood, all body fluids except sweat, non-intact skin, and mucous membranes may carry transmissible organisms even when no infection is diagnosed. As the RN you decide which barriers to use based on the task in front of you, not on the patient's label, so PPE selection is an act of clinical judgment performed dozens of times each shift. The practical core is anticipating exposure. Hand hygiene, gloves, gowns, masks, and eye protection are layered to match the expected contact with fluids and the risk of splash or aerosol. Choosing too little PPE exposes you and the next patient; choosing too much wastes resources and can paradoxically increase contamination during a clumsy doffing sequence. Consider a quick case: you are the nurse assigned to a client with a draining abdominal wound who also needs oral suctioning. Which action protects you and the client first? Before touching anything you anticipate splash and contact, gather gown, gloves, mask, and eye protection, and plan your...