Overview
Overview
Spontaneous abortion, commonly called miscarriage, is pregnancy loss before 20 weeks of gestation.
Spontaneous abortion, commonly called miscarriage, is pregnancy loss before 20 weeks of gestation. In Canada, the 20-week/500-g threshold also marks the vital-statistics boundary used to distinguish a miscarriage from a reportable stillbirth. Most sporadic first-trimester losses arise from fetal chromosomal aneuploidy present from conception, not from exercise, intercourse, work, or minor trauma. Recurrent losses require a broader differential, including antiphospholipid syndrome, uterine abnormalities, endocrine disease, and structural chromosome rearrangements in a parent. Classification depends on four clinical questions: Is the cervix open? Has tissue passed? Is the intrauterine pregnancy viable? Is infection present?
