Overview
Why Pregnancy Changes Clinical Risk
Pregnancy changes glucose handling and cardiovascular workload at the same time.
REx-PN
REx-PN
Pregnancy changes glucose handling and cardiovascular workload at the same time. Placental hormones progressively increase insulin resistance so that more glucose remains available to the fetus. Gestational diabetes mellitus (GDM) develops when maternal insulin production cannot compensate. The patient may feel entirely well, which is why screening and glucose records matter more than symptoms alone. Maternal glucose crosses the placenta; maternal insulin does not. Persistent maternal hyperglycaemia therefore stimulates increased fetal insulin production and can contribute to excessive fetal growth. After birth, the placental glucose supply stops abruptly while the newborn may still have a high insulin level, creating a risk of neonatal hypoglycaemia. Feeding and newborn glucose surveillance are therefore often part of the plan when the pregnancy has been affected by diabetes. Hypertension creates a different but overlapping danger. Elevated vascular resistance can reduce placental perfusion and, when associated with preeclampsia, affect the brain, kidneys, liver, placenta, and fetus. Severe blood pressure is not simply a more abnormal vital sign; it raises the risk of stroke, seizure, placental abruption, and fetal compromise. The nurse notices the blood pressure...
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