Overview
Clinical Meaning
Advanced insulin pump therapy encompasses sensor augmented pump (SAP) therapy, predictive low glucose suspend (PLGS) systems, and hybrid closed loop (HCL) systems that automatic...
CNPLE
CNPLE
Advanced insulin pump therapy encompasses sensor-augmented pump (SAP) therapy, predictive low-glucose suspend (PLGS) systems, and hybrid closed-loop (HCL) systems that automatically adjust basal insulin delivery based on CGM trends. HCL systems use algorithms to increase basal delivery when glucose rises and decrease or suspend delivery when glucose drops, significantly improving time-in-range (3.9–10.0 mmol/L) while reducing hypoglycemia. The clinician prescribes and initiates pump therapy, determines initial basal rates and bolus parameters, adjusts settings based on CGM data and A1C trends, manages perioperative insulin protocols, and handles complex sick day management including DKA prevention. Understanding pump pharmacokinetics, carbohydrate counting accuracy, and algorithm behavior is essential for optimizing outcomes.
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